Chemical-medical interfaces
In our application-oriented, interdisciplinary basic research, we develop new functional polymer materials from bio-based, synthetic and bioinspired polymers, for example, to formulate active ingredients and new biomaterials for contacting biological systems. Controlled crosslinking of synthetic or natural molecular building blocks provides the hydrogels with tunable properties and biological properties associated with (bio)inks for additive manufacturing processes that are required for the construction of artificial articular cartilage or bone.
Main fields of research
Material development
- Functional polymers and hydrogels
- Nano and microparticles (inter alia core-shell particles)
- Ionic polymerization methods (carbanionic and oxyanionic)
- Nano- and microstructured (bio) functional surfaces
- Functional layers for medical and biotechnology
Material processing and material characterization
- Formulation of polymer- and biobased functional (bio)inks for digital 3D printing processes
- Construction of artificial tissue (bioprinting) for 3D tissue engineering for the construction of vascularized tissue
- Tissue-specific bioreactor development
Dissertations
- Development and characterization of surfmer particles as a multifunctional platform for biomolecule conjugation
(Vanessa Albernaz M.Sc., only in english) - Azide-modified extracellular matrix as a biomaterial with variably adjustable properties
(Silke Keller M. Sc., Alumni) - Interfacial functionalization of highly porous hydrogel foams for additive manufacturing.
(Karishma Adatia M. Sc., Alumni, only in german) - Bio-based polymeric adsorber systems for water-soluble substances
(Benjamin Riegger M. Sc., Alumni, only in german) - Printing of novel functional highly porous polymers
(Fabian Schuster M.Sc., Alumni, only in german) - Particulate formulations of carbonhydrate-based bioploymers by spray drying
(Michael Walz M. Sc., Alumni, only in german) - Vascularization of a vascularized bone tissue equivalent using bioprinting technologies
(Annika Wenz M. Sc., Alumni, only in german) - Biomimetic blockcopolymer membranes
(Matthias Bieligmeyer M. Sc., Alumni) - Light-sensitive hydrogel layers for targeted drug release in tissue engineering
(Christiane Claaßen M. Sc., Alumni) - Biomimetic interpenetrating hydrogels for 3D culture of functional zonal cartilage tissue equivalents
Current research projects
- Subretinale Implantation und Verankerung mittels Angiogenese von Polyester-Zellträgern zur retinalen Pigmentepitheltransplantation
- Ersatz herkömmlicher Emulgatoren in Personal-Care-Produkten sowie Wasch- und Reinigungsmitteln durch mikrobiell hergestellte Biotenside
Main fields of research
- Vapor deposition (Chemical Vapor Deposition, CVD)
- Plasma coating and plasma process developments
- Gas phase diagnostics and interface characterization
- Physical-chemical modeling for wetting and wetting, for example for anti-ice surfaces and dry forming
Dissertations
- Funktionale Anti-Eis-Oberflächen durch Plasmabeschichtung (und Mikrostrukturierung) (text in german)
Philipp Grimmer M. Sc., Alumni - Dissertation on OPUS http://dx.doi.org/10.18419/opus-10287 - Selection, characterisation and evaluation of material systems and process options for thermochemical-absorptive heat storage with regard to increasing energy efficiency of industrial processes (text in german)
Mathias Eichler, Alumni - Tests on the continuous dip coating of porous capillary membranes (text in german)
Isabel Jesswein M. Sc., Alumni - Tribosystems for cold forming based on volatile lubricants and laser-structured surfaces (text in german)
Georg Umlauf M. Sc., Alumni
Current research projects
- Tribosystems for cold forming based on volatile lubricants and laser-structured surfaces
(dissertation of Georg Umlauf M. Sc., only in german)
Completed research projects
- ArtiVasc: artificial vascularised scaffolds for 3D tissue regeneration
- Biomaterials for bioprinting – printing of artificial tissue (only in german)
- SynElast: development of a synthetic elastin replacement (only in german)
- WaterMIM: water treatment by molecularly imprinted materials
- Biomimetic process sensor (only in german)
- Glykomik: carbonhydrate modified surface for endo and endo-exo prostheses (only in german)
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Alexander Southan
Dr.Coordination of Chemical-Physical Interfaces // Head of NanoBioMater