Dieses Bild zeigt Steffen Rupp

Steffen Rupp

Herr Prof. Dr.

Institut für Grenzflächenverfahrenstechnik und Plasmatechnologie IGVP


Nobelstr. 12
70569 Stuttgart

Auswahl an Publikationen
  • Günther, M., Grumaz, C., Lorenz, S., Stevens, P., Lindemann, E., Hirth, T., Sohn, K., Zibek, S., Rupp, S. (2015) The transcriptomic profile of Pseudozyma aphidis during production of mannosylerythritol lipids. Appl Microbiol Biotechnol. [Epub ahead of print]
  • Dally S, Rupp S, Lemuth K, Hartmann SC, Hiller E, Bailer SM, Knabbe C, Weile J. (2014) Single-stranded DNA catalyzes hybridization of PCR-products to microarray capture probes. PLoS One. 9(7):e102338.
  • Schwarzmüller, T., Ma, B., Hiller, E., Istel, F., Tscherner, M., Brunke, S., Ames, L., Firon, A., Green, B., Cabral, V., Marcet-Houben, M., Jacobsen, ID., Quintin, J., Seider, K., Frohner, I., Glaser, W., Jungwirth, H., Bachellier-Bassi, S., Chauvel, M., Zeidler, U., Ferrandon, D., Gabaldón, T., Hube, B., d'Enfert, C.*, Rupp, S.*, Cormack, B.*, Haynes, K.*, Kuchler, K.* (2014) Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes. PLoS Pathogens, 10(6):e1004211.
  • Dunkel, N., Biswas, K., Hiller, E., Fellenberg, K., Satheesh, S.V., Rupp, S., Morschhäuser, J. (2014) Control of morphogenesis, protease secretion and gene expression in Candida albicans by the preferred nitrogen source ammonium. Microbiology. 160:1599-608.
  • Berg, M., Michalowski, A., Palzer, S., Rupp, S., Sohn, K. (2014) An In Vivo Photo-Cross-Linking Approach Reveals a Homodimerization Domain of Aha1 in S. cerevisiae. PLoS ONE 9(3): e89436.
  • Lorenz, S., Guenther, M., Grumaz, C., Rupp, S., Zibek, S., Sohn, K. (2014) Genome sequence of the basidiomycetous fungus Pseudozyma aphidis DSM70725, an efficient producer of biosurfactant mannosylerythritol lipids. Genome Announc. 2(1):e00053-14.
  • Seider, K., Brunke, S., Schwarzmüller, T., Barz, D., Rupp, S., Kuchler, K. and Hube, B. (2014) Immune evasion, stress resistance and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryotic Cell, 13(1):170-83.
  • Ludwig, D., Buchmann, M., Hirth, T., Rupp, S. and Zibek, S. (2014) High Solids Enzymatic Hydrolysis of Pretreated Lignocellulosic Materials with a Powerful Stirrer Concept. Appl Biochem Biotechnol, 172:1699–1713.
  • Weishaupt, U., Rupp, S. and Lemuth, K. (2013) Simultaneous detection of different microRNA types using the ZIP-code array system. J Nucleic Acids: 496425.
  • Palige, K., Linde, J., Martin, R., Böttcher, B., Citiulo, F., Sullivan, D.J., Weber, J., Staib, C., Rupp, S., Hube, B., Morschhäuser, J., Staib, P. (2013) Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis. PLoS One;8(4):e61940.
  • Dally, S., Lemuth, K., Kaase, M., Rupp, S., Knabbe, C., Weile, J. (2013) DNA Microarray for Genotyping Antibiotic Resistance Determinants in Acinetobacter baumannii Clinical Isolates. Antimicrob Agents Chemother, 57(10):4761-8.
  • Hogk, I., Kaufmann, M., Finkelmeier, D., Rupp, S. and Burger-Kentischer, A. (2013). An In Vitro HSV-1 Reactivation Model Containing Quiescently Infected PC12 Cells. BioResearch Open Access, 57(10):4761-8.
  • Ludwig D, Amann M, Hirth T, Rupp S, Zibek S. (2013). Development and optimization of single and combined detoxification processes to improve the fermentability of lignocellulose hydrolyzates. Bioresource Technol., 133:455-61.
  • Grumaz, C., Lorenz, S., Stevens, P., Lindemann, E., Schöck, U., Retey, J., Rupp, S., Sohn, K. (2013) Species and condition specific adaptation of the transcriptional landscapes in Candida albicans and Candida dubliniensis.BMC Genomics, 14(1):212.
  • Palzer, S., Bantel, Y., Kazenwadel, F., Berg, M., Rupp, S., Sohn, K. (2013) An Expanded Genetic Code in Candida albicans to study Protein-Protein Interactions in vivo. Eukaryot Cell. 12(6):816-27.
  • Röhm, M., Lindemann, E., Hiller, E., Ermert, D., Lemuth, K., Trkulja, D., Sogukpinar, O., Brunner, H., Rupp, S., Urban, C.F. and Sohn K. (2013) A family of secreted pathogenesis-related proteins in Candida albicans. Mol Microbiol. 87(1):132-51.
  • Moß KS, Hartmann SC, Müller I, Fritz C, Krügener S, Zibek S, Hirth T and Rupp S. (2013) Amantichitinum ursilacus gen. nov., sp. nov., a chitin-degrading bacterium found at the Bärensee, Stuttgart, Germany. Int J Syst Evol Microbiol. 63(Pt 1):98-103.
  • Maestre-Reyna, M., Diderrich, R., Veeldersa, M., Eulenburg, G., Kalugin, V., Brückner S., Keller, P., Rupp, S., Mösch, H.-U., and Essen L.-O. (2012) Structural basis for promiscuity and specificity during Candida glabrata invasion of host epithelia, Proc Natl Acad Sci U S A, 109(42):16864-9
  • Purschke FG, Hiller E, Trick I, Rupp S. (2012) Flexible survival strategies of Pseudomonas aeruginosa in biofilms result in increased fitness compared to Candida albicans. Mol Cell Proteomics. 11(12):1652-69
  • Zavrel, M., Maier, O., Kuchler, K. and Rupp S. (2012) The transcription factor Efg1 shows a haploinsufficiency phenotype in modulating cell wall architecture and immunogenicity of C. albicans. Eukaryotic Cell, 11:129-40
  • Gregori, C., W. Glaser, I.E. Frohner, C. Reinoso-Martin, S. Rupp, C. Schüller and K. Kuchler (2011). Efg1 controls CASP-induced cell aggregation of C. albicans through the Als1 adhesin. Eukaryotic Cell 10:1694-704.
  • Kolecka, A., Zavrel, M., Hernandez-Barbado, R., Rupp, S., Bujdakova, H. (2011) Biofilm formation and adhesive/invasive properties of Candida dubliniensis in comparison with Candida albicans. Central European Journal of Biology, 6 (6), 893-901.
  • Qi-He C, Krügener S, Hirth T, Rupp S, Zibek S (2011) Co-cultured Production of Lignin-Modifying Enzymes with White-Rot Fungi. Appl Biochem Biotechnol. 165(2):700-18
  • Bauer J, Kinast S, Burger-Kentischer A, Finkelmeier D, Kleymann G, Rayyan WA, Schröppel K, Singh A, Jung G, Wiesmüller KH, Rupp S, Eickhoff H. (2011) High-Throughput-Screening-Based Identification and Structure-Activity Relationship Characterization Defined (S)-2-(1-Aminoisobutyl)-1-(3-chlorobenzyl)benzimidazole as a Highly Antimycotic Agent Nontoxic to Cell Lines. J Med Chem. 54(19):6993-7
  • Burger-Kentischer, A., Finkelmeier, D., Keller, P., Bauer, J., Eickhoff, H., Kleymann, G., Rayyan, A., Singh, A., Schröppel, K., Lemuth, K., Wiesmüller, K.H. and Rupp, S. (2011) A screening assay based on host-pathogen interaction models identifies of a set of novel antifungal benzimidazole derivatives. Antimicrob. Agents Chemotherapy, 55(10):4789-801.
  • Luo S, Blom AM, Rupp S, Hipler UC, Hube B, Skerka C, Zipfel PF. (2011)The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem, 286(10):8021-9.
  • Roetzer A, Klopf E, Gratz N, Marcet-Houben M, Hiller E, Rupp S, Gabaldón T, Kovarik P, Schüller C. (2011) Regulation of Candida glabrata oxidative stress resistance is adapted to host environment. FEBS Lett., 585(2):319-27.
  • Schild L, Heyken A, de Groot PW, Hiller E, Mock M, de Koster C, Horn U, Rupp S, Hube B. (2011) Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell, 10(1):98-109.
  • Ludwig, D., Amann, M., Hirth, T., Rupp, S. und Zibek, S. (2010) Laccase-katalysierte Detoxifizierung von löslichen Ligninabbauprodukten in vorbehandelten Lignocellulose-Hydrolysaten. Ing. Tech., 82,1183-1189.
  • Günther, M., Zibek, S., Hirth, T. und Rupp, S. (2010) Synthese und Optimierung von Cellobioselipiden und Mannosylerythritollipiden. Ing. Tech., 82, 1215-1221.
  • Calderon, J., Zravel, M., Ragni, E., Fonzi, W.A., Rupp, S., and Popolo, L. (2010) Cell wall glucan remodeling is required for Candida albicans adhesion and invasion. Microbiology, 156: 2484-94.
  • Burger-Kentischer, A., Abele, I.S., Finkelmeier, D., Wiesmüller, K.H. and Rupp, S. (2010) A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens. Journal of Immunological Methods, 358(1-2):93-103.
  • Lindemann, E., Rohde, B., Rupp, S., Regenbogen, J. and Sohn, K. (2010)
    A Multidimensional Electrophoretic System of Separation for the Analysis of Gene Expression (MESSAGE). Electrophoresis, 31(8):1330-43.
  • Brunke, S.; Seider, K.; Almeida, R.S.; Heyken, A.; Fleck, C.B.; Brock, M.; Barz, D.; Rupp, S. and Hube B. (2010) Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol, Apr;76(1):25-47.
  • Luo, S., Poltermann, S., Kunert, A., Rupp, S. and Zipfel PF. (2009). Immune evasion of the human pathogenic yeast Candida albicans: Pra1 is a Factor H, FHL-1 and plasminogen binding surface protein. Mol. Immunol. 47(2-3):541-50.
  • Zibek, S., Huf S., Wagner, W., Hirth, T. and Rupp, S. (2009) Fermentative Herstellung der ,-Dicarbonsäure 1,18-Oktadecendisäure als Grundbaustein für biobasierte Kunststoffe. Ing. Tech. 11: 1797-1808.
  • Xiong, X.; Ghosh, R.; Hiller, E.; Drepper, F.; Knapp, B.; Brunner, H. and Rupp, S. (2009). A new procedure for rapid, high yield purification of Type I collagen for tissue engineering. Process Biochemistry 44 (11): 1200-1212.
  • Hauser, N.C., Dukalska, M., Fellenberg, K. and S. Rupp (2009) From experimental setup to data analysis in transcriptomics: copper metabolism in the human pathogen Candida albicans. Journal of Biophotonics, 2(4):262-8.
  • Bareiss, P.M., M. Metzger, K. Sohn, S. Rupp, J.S. Frick, I.B. Autenrieth, F. Lang, H. Schwarz, T. Skutella, and L. Just (2008) Organotypical tissue cultures from adult murine colon as an in vitro model of intestinal mucosa. Histochem Cell Biol. 129(6): 795-804.
  • Wilson, D., A. Tutulan-Cunita, W. Jung, N.C. Hauser, R. Hernandez, T. Williamson, K. Piekarska, S. Rupp, T. Young, and L. Stateva (2007) Deletion of the high-affinity cAMP phosphodiesterase encoded by PDE2 affects stress responses and virulence in Candida albicans. Mol. Microbiol 65(4): 841-56.
  • Hiller E, Heine S, Brunner H, Rupp S (2007) Candida albicans Sun41p, a Putative Glycosidase, Is Involved in Morphogenesis, Cell Wall Biogenesis, and Biofilm Formation. Eukaryot. Cell 6: 2056-2065
  • Lammle K, Zipper H, Breuer M, Hauer B, Buta C, Brunner H, Rupp S (2007) Identification of novel enzymes with different hydrolytic activities by metagenome expression cloning. J Biotechnol 127: 575-592.
  • Hauser, N.C., Martinez, R., Jacob, A., Rupp, S., Hoheisel, J.D. and Matysiak, S. (2006) Utilising the left-helical conformation of L-DNA for analysing different marker types on a single universal microarray platform. Nucleic Acids Res, 34: 5101-5111.
  • Borchers, K., Weber, A., Hiller, E., Rupp, S., Brunner, H. and Tovar, G.E.M. (2006) Nanoparticle-based Diagnostic 3D-Protein-Biochip for Candida albicans. PMSE Preprints, 95, 1016-1017.
  • Sohn, K., Senyürek, I., Fertey, J., Königsdoefer, A., Joffroy, C., Hauser, N., Zelt, G., Brunner, H., and Rupp, S. (2006) An in vitro-assay to study the transcriptional response during adherence of Candida albicans to different human epithelia. FEMS Yeast Research, 6: 1085-93.
  • Sohn, K., Hauser, N., Brunner, H., and Rupp, S. (2006) Cell wall dynamics and transcriptional response in Candida albicans during morphogenesis and adhesion to mammalian epithelia. Mycoses, 5: 352.
  • Sohn K., Schwenk J., Urban C., Lechner J., Schweikert M., Rupp S. (2006). Getting in touch with Candida albicans the cell wall of a fungal pathogen. Curr Drug Targets, 7(4):505-12.
  • Carter, G. Rupp, S. Fink, G., Galitski, T. (2006). Disentangling inform-ation flow in the Ras-cAMP signaling network. Genome, 16(4):520-6.
  • Sohn, K., Roehm, M., Urban, C., Saunders, N., Rothenstein, D., Lottspeich, F., Schröppel, K., Brunner, H. and Rupp, S. (2005). Identification and Characterization of Cor33p, a protein implicated in tolerance towards oxidative stress in Candida albicans, Eukaryotic cell, 4(12):2160-2169.
  • Urban, C., Xiong, X., Sohn, K., Schröppel, K., Brunner, H. and Rupp, S. (2005) The Moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicans, Mol Microbiol, 57(5):1318-41.
  • Maidan, M.M., De Rop, L., Serneels, J., Exler, S., Rupp, S., Tournu, Thevelein, J.M., and Van Dijck, P. (2005) The G Protein-coupled Receptor Gpr1 and the G{a} Protein Gpa2 Act through the cAMP-PKA Pathway to Induce Morphogenesis in Candida albicans. Mol Biol Cell. 16 (4): 1971-86.
  • Hauser, N.C., Zeller, Z., Brunner, H., Tovar, G. and Rupp, S. (2004) Array-Techniken zur Diagnostik von human-pathogenen Pilzen. Mycoses 47/8: 362.
  • Lotz, H., Sohn, K., Brunner, H., Mühlschlegel F.A., and Rupp, S. (2004) RBR1, a novel pH regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1. Eukaryotic Cell, 3, 776-784.
  • Hauser, N.C., Teifel, S., Buck, M., Fellenberg, K., Wajant, H., Rupp, S. and Knabbe, C. (2003) DNA-Chip for diagnostic purposes in breast cancer. Clin Chem and Lab Med, 41(10): 97.
  • Urban, C., Sohn, K., Lottspeich, F., Brunner, H. and Rupp, S. (2003) Identification of cell surface determinants in Candida albicans reveals Tsa1p, a protein differentially localized in the cell, FEBS Lett., 544, 229-236.
  • Rottmann, M., Dieter, S., Brunner, H. and Rupp, S. (2003) CaMCM1 is an essential gene in C. albicans, crucial for morphogenesis. Mol Microbiol, 47: 943-59.
  • Sohn, K., Urban, C., Brunner, H. and Rupp, S. (2003) EFG1 is a major regulator of cell wall dynamics in Candida albicans as revealed by DNA microarrays. Mol Microbiol, 47: 89-102.
  • Dieterich, C., Schandar, M., Noll, M, Johannes, F.-J., Brunner, H., Graeve, T. and Rupp, S. (2002). In vitro reconstructed human epithelia reveal contributions of Candida albicans EFG1 and CPH1 to adhesion and invasion. Microbiology, 148: 497-506.
  • Brandlin, I., Hubner, S., Eiseler, T., Martinez-Moya, M., Horschinek, A., Hausser, A., Link, G., Rupp, S., Storz, P., Pfizenmaier, K., and Johannes, F. J. (2002). Protein kinase C (PKC) eta-mediated PKC m activation modulates ERK and JNK signal pathways, J Biol Chem, 277: 6490-6.
  • Rupp, S. (2000). Differenzielle Proteomanalyse zur Identifizierung von Virulenzfaktoren bei Candida albicans. Mycoses, 43: 251-2.
  • Schweizer, A., Rupp, S., Taylor, B. N., Röllinghoff, M. and Schröppel, K. (2000). The TEA/ATTS transcriptionfactor CaTec1p regulates hyphal development and virulence in Candida albicans. Mol Microbiol, 38: 435-45.
  • Fotin-Mleczek, M., Rottmann, M., Rehg, G., Rupp, S. and Johannes, F. J. (2000). Detection of protein-protein interactions using a green fluorescent protein-based mammalian two-hybrid system. Biotechniques, 29: 22-6.
  • Joos, T. O., Schrenk, M., Hopfl, P., Kroger, K., Chowdhury, U., Stoll, D., Schorner, D., Durr, M., Herick, K., Rupp, S., Sohn, K. and Hammerle, H. (2000). A microarray enzyme-linked immunosorbent assay for autoimmune diagnostics. Electrophoresis, 21: 2641-50.
  • Kontoyiannis, D. P. and Rupp, S. (2000). Cyclic AMP and fluconazole resistance in Saccharomyces cerevisiae. Antimicrob Agents Chemother, 44: 1743-4.
  • Rupp, S., Summers, E., Lo, H. J., Madhani, H., and Fink, G. (1999). MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene. Embo J, 18: 1257-69.
  • Kubler, E., Mosch, H. U., Rupp, S. and Lisanti, M. P. (1997) Gpa2p, a G-protein alpha-subunit, regulates growth and pseudohyphal development in Saccharomyces cerevisiae via a cAMP-dependent mechanism. J Biol Chem, 272: 20321-3.
  • Rupp, S. and Wolf, D. H. (1995). Biogenesis of the yeast vacuole (lysosome). The use of active-site mutants of proteinase yscA to determine the necessity of the enzyme for vacuolar proteinase maturation and proteinase yscB stability, Eur J Biochem, 231: 115-25.
  • Rupp, S. and Wolf, D. H. (1993). Biogenesis of the yeast vacuole (lysosome). Signal sequence deletion of the vacuolar aspartic proteinase yscA does not block maturation of vacuolar proteinases, Biol Chem Hoppe Seyler, 374: 1109-15.
  • Rupp, S., Hirsch, H. H. and Wolf, D. H. (1991). Biogenesis of the yeast vacuole (lysosome). Active site mutation in the vacuolar aspartate proteinase maturation of vacuolar proteinases, FEBS Lett, 293: 62-6.  
    • Rupp, S. (2013) New bioproduction systems: from molecular circuits to novel reactor concepts in cell-free biotechnology, Adv Biochem Eng Biotechnol., 137:103-23.
    • Rupp, S. (2013) Next-generation bioproduction systems: Cell-free conversion concepts for industrial biotechnology. Engineering in Life Sciences, 13, 19–25.
    • Hiller, E., Zavrel, M., Hauser, N., Sohn, K., Burger-Kentischer, A., Lemuth, K., Rupp, S. (2011) Adaptation, adhesion and invasion during interaction of Candida albicans with the host-focus on the function of cell wall proteins. Int J Med Microbiol 301:384-389.
    • Rupp, S., An approach to characterize the membrane proteome of Candida albicans. (2010): Future Microbiol. 5(2): 147-151.
    • Hirth, T., S. Rupp and W. Trösch, Bereitstellung von Energie und Rohstoffen für eine den biogenen Stoffkreisläufen nachempfundene, nachhaltige Stoffwirtschaft. Eine neue Herausforderung für die Bioverfahrenstechnik? (2009): Ing. Tech. 81 (11): 1582-1597.
    • Rupp, S., (2007) Interactions of the fungal pathogen albicans with the host,
      Future Medicine, 2: 141-151.
    • Sohn, K., Schwenk, J., Urban, C., Lechner, J., Schweikert, M. Rupp, S. (2006) Getting in touch with Candida albicans: the cell wall of a fungal pathogen. Current Drug Targets, 7: 505-12.
    • Rupp, S. und Hauser, N.C. (2005) DNA-Chip Technologien zur Untersuchung der Wirt-Pathogen-Interaktion bei C. albicans. BIO Spektrum, 11: 513-515.
    • Rupp S. (2004a) Proteomics on its way to study host-pathogen interaction.
      Current Opinion in Microbiology 7: 330-335
    • Rupp, S. (2004b) Die Zellwand von C. albicans als Schnittstelle zwischen Wirt und Pathogen. Hygiene und Mikrobiologie, 2: 46-51.
    • Hauser, N., Weber, A., Tovar, G. & Rupp, S. (2003) Nanopartikel-Biochips zur Untersuchung von albicans. Biospektrum, 9: 710-712
    • Hauser, N. C., Fellenberg, K. and Rupp, S. (2002). How to Discover Pathogenic Mechanisms - New Evaluation Tools Towards Drug Discovery. Screening, 3: 28-31.
    • Rupp, S. (2000). Identifizierung von Virulenzfaktoren in Hefen, Bioworld, 3: 21-23.
    • Knop, M., Schiffer, H. H., Rupp, S. and Wolf, D. H. (1993). Vacuolar/lysosomal proteolysis: proteases, substrates, mechanisms, Curr Opin Cell Biol, 5: 990-6.
    • Lemuth, K. and Rupp, S. (2015). Microarrays as research tools and diagnostic devices, in RNA and DNA diagnostics. Springer, Eds. Erdmann, V.; Jurga, S.; Barciszewski, J. in press.
    • Hogk, I., Rupp, S. and Burger-Kentischer, A. (2013). 3D Tissue Model for Herpes Simplex Virus-1 Infections, Methods in Molecular Biology, 1064:, Eds.: Bailer, S. M.; Lieber, D..
    • Moss, K., Zibek, S. Hirth, T. and Rupp, S. (2010) Chitin converting enzymes, submitted.
    • Zibek, S., Rupp, S., (2009) Enzyme – Moderne Werkzeuge der Biotechnologie, Analysen und Expertisen zur Wehrtechnischen Vorausschau, FhG INT, Euskirchen.
    • Sohn, K. and S. Rupp, Human epithelial model systems for the study of Candida infections in vitro: part I. Adhesion to epithelial models. Methods Mol Biol, 2009. 470: 95-104.
    • Rupp, S., Introduction: fungal pathogens. Methods Mol Biol, 2009. 470: 69-70.
    • Hernandez, R. and S. Rupp, Human epithelial model systems for the study of Candida infections in vitro: part II. Histologic methods for studying fungal invasion. Methods Mol Biol, 2009. 470: 105-23.
    • Sohn, K, Hiller, E , Rupp, S., 2008, Proteomics Sample Preparation, Sample Preparation for the Cell-Wall Proteome Analysis of Yeast and Fungi, J. von Hagen, Wiley-Vch. 371-378.
    • Rupp, S. (2008) Transcriptomics of the fungal pathogens focusing on albicans, The Mycota, 7, 2 nd Edition, “Human and Animal Relationships”, 187-222.
    • Sohn, K., Hauser, N. C. and Rupp, S. (2002). Proteomics, genomics and molecular genetics to study fungal development, Recent Res. Devel. in Mol. Microbiol., 1: 45-70, Research Signpost, Ed. S.G. Pandalai, Kerala, India.
    • Rupp, S. (2002) LacZ assays in Yeast, Methods in Enzymology, 350: 112-131.
    • Rupp, S., Johannes, F.-J. und Komischke, K., (2001): Biochips – Moderne Werkzeuge der Biotechnologie, Analysen und Expertisen zur Wehrtechnischen Vorausschau, FhG INT, Euskirchen.

    Host-Pathogen Interactions, (2009), Methods Mol Biol, Humana Press, Editors Steffen Rupp and Kai Sohn.


    EP000001290144A2: INFECTION MODEL

Akademischer Werdegang

Mai 2015 Ernennung zum apl. Professor für Molekulare Biotechnologie der Universität Stuttgart
Seit 2011 Promotionsrecht an der Universität Stuttgart
2000 – 2004 Habilitation an der Universität Stuttgart, Thema der Habilitationsschrift: 
»Signaltransduktions-Mechanismen bei der Morphogenese und Pathogenese von Hefen«
1990 – 1994 Promotion am Institut für Biochemie der Universität Stuttgart, Thema der Dissertation:
»Aufklärung der Aktivierungsmechanismen vakuolärer Proteinasen der Hefe Saccharomyces cerevisiae mit Hilfe von Mutationsstudien des aktiven Zentrums der Aspartat-Proteinase yscA«
1989 – 1991 Diplomarbeit am Institut für Biochemie und Molekularbiologie der Universität Freiburg, Medizinische Fakultät Thema der Diplomarbeit: »Biogenese der Vakuole (des Lysosoms) der Hefe Saccharomyces cerevisiae: Studien an einer Mutation des aktiven Zentrums der Proteinase yscA«
1986 – 1987 Aufenthalt an der University of Cincinnati, Organic Department, im Rahmen eines Stipendiums des Deutschen Akademischen Austauschdienstes (DAAD).  Abschluss: Master of Science, MSc.
1982–1990 Chemiestudium an der Universität Stuttgart Abschluss: Diplom


Seit April 2015 Stellvertretender Institutsleiter am Fraunhofer IGB
Seit Januar 2006 Abteilungsleiter Molekulare Biotechnologie am Fraunhofer IGB
Seit 2004 Privatdozent an der Universität Stuttgart
1999 – 2005 Leiter der Nachwuchsforschergruppe „Automatisierte Proteinscreening Systeme“ am Fraunhofer-Institut
1995 – 1998 Forschungsaufenthalt in USA Wissenschaftlicher Mitarbeiter am Whitehead Institute for Biomedical Research, MIT, Cambridge, USA


Seit 2014 Fakultät Energie-, Verfahrens- und Biotechnik, Universität Stuttgart
  • Biologische und chemische Verfahren für die industrielle Nutzung von Biomasse (mit Dr. Schliessmann)
  • Infektionsbiology: Pathogenese und Diagnostik von Pilzen
Seit 2011 Fakultät Energie-, Verfahrens- und Biotechnik, Universität Stuttgart
  • Teile der Medizinischen Verfahrenstechnik II
  • Medizinische und Molekulare Diagnostik (1 SWS)
  • Biobasierte Materialien (2 SWS, mit Prof. Hirth) 
von 1999 – 2011 Fakultät Chemie, Institut für Biochemie Universität Stuttgart
  • Moderne Methoden in der Biochemie
  • Ausgewählte Kapitel in der Biochemie
  • Seminar zum Großpraktikum Biochemie


  • Biochemisches Praktikum für Technische Biologen
  • Biochemisches Praktikum für Dipl. Chemiker (Wahlpflichtfach-Praktikum)

 Mitarbeit in Fachverbänden und Gremien

  • Gesellschaft für Biologische Chemie, GBM
  • Deutsche Gesellschaft für Hygiene und Mikrobiologie, DGHM
  • Deutschsprachige Mykologische Gesellschaft eV., DMykG
  • Verbindungsmann der GBM für die Universität Stuttgart (seit 2008)
  • Gewähltes Mitglied des FEBS Advanced Courses Committee (2009–2014)
  • Gewähltes Mitglied im Vorstand der Fachgruppe »Eukaryonte Pathogene« der DGHM (2009–2012)
  • Mitglied des Experten-Kreises für »Next Generation Biotechnology« des BMBF
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